Since the cold weather has hit here in the northeast my radio has been acting up When I first start the car the radio will play through all 6 speakers after a few mins the left door speaker and the left mid range will stop, also the back rear right speaker will stop working also. So at this time I only have 3 speakers working I was told it might be a ground issue? please help its driving me nuts lol

 

It sounds like the Bose head unit to me. What you are experiencing is very similar to what my Bose head unit did. I would lose one speaker then another and another. And it was different for when I was playing the radio or the CD.

I would be amazed if you have the original head unit in your car. You're lucky if they last 10 years. E-bay is a good place to get a replacement.